HCID 22710058, compound → 1-[(6-Chloronaphthalen-2-yl)sulfonyl]-4-[4-(pyridin-3-yl)benzoyl]piperazine hydrochloride

HRID 1061058Notes

Reaction equation

HRID 1061058 reaction equation
Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[C:4]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=O)=[CH:10][CH:9]=2)[CH:3]=1.FC(F)(F)C(O)=O.[Cl:24][C:25]1[CH:26]=[C:27]2[C:32](=[CH:33][CH:34]=1)[CH:31]=[C:30]([S:35]([N:38]1[CH2:43][CH2:42][NH:41][CH2:40][CH2:39]1)(=[O:37])=[O:36])[CH:29]=[CH:28]2>>[ClH:24].[Cl:24][C:25]1[CH:26]=[C:27]2[C:32](=[CH:33][CH:34]=1)[CH:31]=[C:30]([S:35]([N:38]1[CH2:39][CH2:40][N:41]([C:12](=[O:14])[C:11]3[CH:10]=[CH:9][C:8]([C:4]4[CH:3]=[N:2][CH:7]=[CH:6][CH:5]=4)=[CH:16][CH:15]=3)[CH2:42][CH2:43]1)(=[O:36])=[O:37])[CH:29]=[CH:28]2

Participants

3

Reactant 2

HCID 22710058HCID 22710058, compoundHCID 694831834-(Pyridin-3-YL)benzoic acid hydrochloride

Product 1

HCID 227110191-[(6-Chloronaphthalen-2-yl)sulfonyl]-4-[4-(pyridin-3-yl)benzoyl]piperazine hydrochloride

Procedure

In a similar manner to Example 4 except for the use of 4-(3-pyridyl)benzoic acid hydrochloride and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine trifluoroacetate as the raw materials, the reaction was conducted, whereby the title compound was obtained as a colorless solid.

Sources & evidence

ORD record
ord-606ddc4098004e398903a20dc47b123d
Source dataset
uspto-grants-2003_02
Patent number
US06525042B1

Reaction notes

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