5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carboxylic acid → HCID 22709602, compound

HRID 1061078Notes

Reaction equation

HRID 1061078 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11]2[S:14][C:15]([C:17]([OH:19])=O)=[CH:16][C:10]=2[CH2:9]1)=O)(C)(C)C.FC(F)(F)C(O)=O.[Cl:27][C:28]1[CH:29]=[C:30]2[C:35](=[CH:36][CH:37]=1)[CH:34]=[C:33]([S:38]([NH:41][CH:42]1[CH2:47][CH2:46][NH:45][CH2:44][CH2:43]1)(=[O:40])=[O:39])[CH:32]=[CH:31]2>>[ClH:27].[Cl:27][C:28]1[CH:29]=[C:30]2[C:35](=[CH:36][CH:37]=1)[CH:34]=[C:33]([S:38]([NH:41][CH:42]1[CH2:47][CH2:46][N:45]([C:17]([C:15]3[S:14][C:11]4[CH2:12][CH2:13][NH:8][CH2:9][C:10]=4[CH:16]=3)=[O:19])[CH2:44][CH2:43]1)(=[O:39])=[O:40])[CH:32]=[CH:31]2

Participants

3

Reactant 2

HCID 177503995-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carboxylic acidHCID 22711385HCID 22711385, compound

Product 1

HCID 22709602HCID 22709602, compound

Procedure

In a similar manner to Example 4 except for the use of 5-tert-butoxycarbonyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-carboxylic acid and 4-[(6-chloronaphthalen-2-yl)sulfonamido]piperidine trifluoroacetate as the raw materials, the reaction was conducted, whereby the title compound was obtained.

Sources & evidence

ORD record
ord-f1b20ebe3d3543e78d2fabc0a5ca3f45
Source dataset
uspto-grants-2003_02
Patent number
US06525042B1

Reaction notes

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