Borane;tetrahydrofuran → HCID 69655076, compound

Participants

Reaction Steps

The title compound was prepared from N-[4-(2-bromoacetyl)phenyl]methanesulfonamide (0.23 g, 0.82 mmol )(which was obtained in Example 111), and 1M BH3/THF solution (10.35 mL, 10.5 mmol) in substantially the same manner, as described in Example 103 and was obtained as a white solid (1.75 g, 72% yield); MS (ES) m/z: 293 (M)+; 1H NMR (400 MHz, DMSO-d6) δ 7.14 (d, 2H), 2.95 (s, 3H), 3.53 (m, 1H), 3.55 (m, 1H), 4.73, (m, 1H), 5.75 (d, 1H), 7.14 (d, 2H), 9.74 (s, 1H).

Provenance & Evidence