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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1061300Generated: October 26, 2026

Glycine methyl ester hydrochloride → Methyl {[4-(4-oxo-1-piperidineyl)benzoyl]amino}acetate

https://huagongshe.com/reaction/1061300

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycine methyl ester hydrochlorideHCID 122755—
Reactant4-(4-Oxopiperidin-1-yl)benzoic acidHCID 22064022—
ProductMethyl {[4-(4-oxo-1-piperidineyl)benzoyl]amino}acetateHCID 86584566—

Reaction Steps

The title compound was prepared from 4-(4-oxo-piperidine-1-yl)-benzoic acid (which was obtained in Example 151) and glycine methyl ester hydrochloride according to the procedure of Example 154 as a gum; MS (ES) m/z: 291.3 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06525202B2
Source datasetuspto-grants-2003_02
ORD IDord-3a99bbd322314cd99985c9cb17c6cebb
Source noteuspto-grants-2003_02