N-[2-Benzyloxy-5-(2-dibenzylamino-1-hydroxy-ethyl)-phenyl]-methanesulfonamide → HCID 22220304, compound

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Reaction Steps

The title compound was prepared from N-{4-[4-(4-oxo-piperidine-1-yl)-phenylsulfamoyl]-phenyl}-acetamide (which was obtained in Example 216) and N-[2-benzyloxy-5-(2-dibenzylamino-1-hydroxy-ethyl)-phenyl]-methanesulfonamide (which was obtained in Example 7) according to the procedure of Example 255 as a yellowish solid; 1H NMR (300 MHz, DMSO-d6) δ 1.35-1.60 (m, 2H), 1.90-2.10 (m, 2H), 2.06 (s, 3H), 2.50-3.00 (m, 5H), 3.16 (s, 3H), 3.55-3.70 (m, 2H), 4.65-4.80 (m, 1H), 6.00 (brs, 1H), 6.70-7.25 (m, 7H), 7.58 (d, J=9.0 Hz, 2H), 7.68 (d, J=9.0 Hz, 2H), 10.39 (s, 1H); MS (ES) m/z: 618.1 (MH+); HRMS Calcd. for C28H36N5O7S2 (MH+): 618.2056. Found: 618.2036.

Provenance & Evidence