4-Amino-5-chloro-thiophene-2-sulfonic acid (2-hydroxy-ethyl)-amide → 5-(3-Ethoxy-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [2-chloro-5-(2-hydroxy-ethylsulfamoyl)-thiophen-3-yl]-amide
Reaction equation
[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6](-[c:14]2[n:15][c:16]3[n:17]([c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[n:24][cH:25][c:26]3[C:27](=[O:28])[OH:29])[cH:7][cH:8][c:9]1[C:10]([F:11])([F:12])[F:13].[OH:30][CH2:31][CH2:32][NH:33][S:34](=[O:35])(=[O:36])[c:37]1[s:38][c:39]([Cl:43])[c:40]([NH2:42])[cH:41]1>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6](-[c:14]2[n:15][c:16]3[n:17]([c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[n:24][cH:25][c:26]3[C:27](=[O:28])[NH:42][c:40]2[c:39]([Cl:43])[s:38][c:37]([S:34]([NH:33][CH2:32][CH2:31][OH:30])(=[O:35])=[O:36])[cH:41]2)[cH:7][cH:8][c:9]1[C:10]([F:11])([F:12])[F:13]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-e1f2abb66fc7470ba7eb9d1b812cbe2e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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