(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine → 1-(2-methoxy-5-trifluoromethoxybenzoyl)-3-(2-(4-(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl-amino)piperidin-1-yl)ethyl)-3-phenylpyrrolidine

HRID 106165Notes

Reaction equation

HRID 106165 reaction equation
[CH2:34]([CH3:35])[O:36][CH2:37][CH2:38][n:39]1[c:40]([NH:48][CH:49]2[CH2:50][CH2:51][NH:52][CH2:53][CH2:54]2)[n:41][c:42]2[c:43]1[cH:44][cH:45][cH:46][cH:47]2.[CH3:1][O:2][c:3]1[c:4]([C:5](=[O:6])[N:7]2[CH2:8][C:9]([CH2:12][CH2:13][O:14][S:15]([CH3:16])(=[O:17])=[O:18])([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH2:10][CH2:11]2)[cH:25][c:26]([O:29][C:30]([F:31])([F:32])[F:33])[cH:27][cH:28]1>>[CH3:1][O:2][c:3]1[c:4]([C:5](=[O:6])[N:7]2[CH2:8][C:9]([CH2:12][CH2:13][N:52]3[CH2:51][CH2:50][CH:49]([NH:48][c:40]4[n:39]([CH2:38][CH2:37][O:36][CH2:34][CH3:35])[c:43]5[c:42]([n:41]4)[cH:47][cH:46][cH:45][cH:44]5)[CH2:54][CH2:53]3)([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH2:10][CH2:11]2)[cH:25][c:26]([O:29][C:30]([F:31])([F:32])[F:33])[cH:27][cH:28]1

Participants

3

Reactant 2

HCID 13808350(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amineHCID 220092811-(2-Methoxy-5-trifluoromethoxybenzoyl)-3-phenyl-3-(2-methanesulfonyloxyethyl)pyrrolidine

Product 1

HCID 536747301-(2-methoxy-5-trifluoromethoxybenzoyl)-3-(2-(4-(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl-amino)piperidin-1-yl)ethyl)-3-phenylpyrrolidine

Sources & evidence

ORD record
ord-76e69e09729047f5a3e783bfc025f33f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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