HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1061659Generated: October 26, 2026
Acetic Anhydride → 4-Benzyl-2-phenyl-2-oxazolin-5-one
https://huagongshe.com/reaction/1061659
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | N-Benzoyl-DL-phenylalanine | HCID 273362 | — |
| Product | 4-Benzyl-2-phenyl-2-oxazolin-5-one | HCID 2756650 | 85.5% |
Reaction Steps
A suspension of N-benzoyl-DL-phenylalanine (5.39 g) and acetic anhydride (12.3 g) is stirred at 80° C. for 40 minutes under a nitrogen atmosphere. The reaction mixture is concentrated under reduced pressure to give the titled reference compound (4.30 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06960575B2 |
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| Source dataset | uspto-grants-2005_11 |
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| ORD ID | ord-92de09d394204087a6759572d4dc5add |
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| Source note | uspto-grants-2005_11 |
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