HCID 22285724, compound → HCID 22285725, compound

HRID 1061730Notes

Reaction equation

HRID 1061730 reaction equation
[N+:1]([C:4]1[C:12]2[N:11]([CH2:13][CH:14]([OH:16])[CH3:15])[N:10]=[C:9]3[CH2:17][CH2:18][CH2:19][C:7]([C:8]=23)=[CH:6][CH:5]=1)([O-])=O>C(O)C>[NH2:1][C:4]1[C:12]2[N:11]([CH2:13][CH:14]([OH:16])[CH3:15])[N:10]=[C:9]3[CH2:17][CH2:18][CH2:19][C:7]([C:8]=23)=[CH:6][CH:5]=1

Participants

3

Reactant 1

HCID 22285724HCID 22285724, compound

Product 1

HCID 22285725HCID 22285725, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of the product from Step B (0.85, 3.3 mmol) in ethanol was treated as described for Step D of Example 1 to provide a solid (0.71 g, 99%): m.p 129-131° C.; MS (ES) m/z 232 (M+); 1H NMR (DMSO-d6) δ 7.03 (1H, d, J=8.0 Hz), 6.72 (1H, d, J=8.0 Hz), 4.80 (1H, d, J=4.0 Hz), 4.51(2H, brs), 4.01 (3H, m), 2.78 (2H, t, J=6.0 Hz), 2.62 (2H, t, J=6.0 Hz), 2.02 (2H, m), 1.00 (3H, d, J=6.0 Hz).

Sources & evidence

ORD record
ord-0acb634fc4b04d05af32f2648f6e24a7
Source dataset
uspto-grants-2005_11
Patent number
US06960608B2

Reaction notes

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