Sulfuric acid hydrate (1:1) → HCID 22285712, compound

HRID 1061731Notes

Reaction equation

HRID 1061731 reaction equation
N[C:2]1[C:10]2[N:9]([CH2:11][CH:12]([OH:14])[CH3:13])[N:8]=[C:7]3[CH2:15][CH2:16][CH2:17][C:5]([C:6]=23)=[CH:4][CH:3]=1.[OH:18]S(O)(=O)=O.O>>[OH:14][CH:12]([CH3:13])[CH2:11][N:9]1[C:10]2=[C:2]([OH:18])[CH:3]=[CH:4][C:5]3=[C:6]2[C:7]([CH2:15][CH2:16][CH2:17]3)=[N:8]1

Participants

3

Reactant 2

HCID 21910475Sulfuric acid hydrate (1:1)HCID 22285725HCID 22285725, compound

Product 1

HCID 22285712HCID 22285712, compoundYield 86%

Procedure

The product from Step C (0.70 g, 3.2 mmol) was dissolved in H2SO4/H2O (1:2, 30 mL) and treated as described in Step E of Example 1 to provide a solid (0.60 g, 86%): m.p 162-163° C.; MS (ES) m/z 233(M+).

Workup

  1. additiontreated

Sources & evidence

ORD record
ord-3739dc6a5fe54c2bab3777da6c5bf264
Source dataset
uspto-grants-2005_11
Patent number
US06960608B2

Reaction notes

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