HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethyl borate → [2-Fluoro-3-(pyridin-4-yl)phenyl]boronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethyl borate | HCID 8470 | — |
| Reactant | 4-(2-Fluorophenyl)pyridine | HCID 13270646 | — |
| Product | [2-Fluoro-3-(pyridin-4-yl)phenyl]boronic acid | HCID 22285310 | — |
Reaction Steps
4-(2-Fluorophenyl)pyridine was lithiated and reacted with trimethyl borate as described in Example 11 to afford 2-fluoro-3-(pyridin-4-yl)benzeneboronic acid as a white solid: m/z (ES+) 218 (M++H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960598B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-88e3d7e954414669982e2ad695f05f33 |
| Source note | uspto-grants-2005_11 |