Water → HCID 10428321, compound

Participants

Reaction Steps

Bromine (86 mg, 0.54 mmol) in acetic acid (2 mL) was added dropwise into solution of 2-(6-hydroxy-1-naphthyl)-1,3-benzoxazol-6-ol (0.15 g, 0.54 mmol) and acetic acid (9 mL). The reaction mixture was stirred for 2 h, poured into water and the precipitated solid filtered and dried. The product was recrystallized from acetone/EtOAc to give a yellow solid, m.p. 221-223° C.; MS m/e 354 (M−H)+

Provenance & Evidence