HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Fluoro-2-methylphenyl)boronic acid → HCID 69592874, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Fluoro-2-methylphenyl)boronic acid | HCID 2734665 | — |
| Reactant | Tert-butyl (4-iodo-2-nitrophenyl)carbamate | HCID 23554339 | — |
| Product | HCID 69592874 | HCID 69592874 | — |
Reaction Steps
Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and 4-fluoro-2-methylbenzene boronic acid [CAS-no. 139911-29-8; prepared from 2-bromo-5-fluorotoluene by reaction with n-BuLi at −78° C. followed by treatment with B(OMe)3 and subsequent hydrolysis] according to the general procedure B. Obtained as a yellow solid (1.71 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960578B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-e8448e90bcf146e39ce7c30aa4092fb8 |
| Source note | uspto-grants-2005_11 |