HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Fluoro-2-iodobenzene → [4-(2-Fluoro-phenylethynyl)-2-nitro-phenyl]-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Fluoro-2-iodobenzene | HCID 67673 | — |
| Reactant | tert-Butyl (4-ethynyl-2-nitrophenyl)carbamate | HCID 23554338 | — |
| Product | [4-(2-Fluoro-phenylethynyl)-2-nitro-phenyl]-carbamic acid tert.-butyl ester | HCID 69592787 | 106.5% |
Reaction Steps
Prepared from (4-ethynyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example F2) (525 mg, 2.0 mmol) and 2-fluoro-1-iodobenzene (0.35 mL, 3 mmol) according to the general procedure F. Obtained as a yellow solid (759 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960578B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-96d3b6400e0b4fd0868bd2fd00e2d502 |
| Source note | uspto-grants-2005_11 |