(4-Naphthalen-1-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester → (2-Amino-4-naphthalen-1-yl-phenyl)-carbamic acid tert.-butyl ester

HRID 1061962Notes

Reaction equation

HRID 1061962 reaction equation
[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH:17]=[CH:16][CH:15]=2)=[CH:10][C:9]=1[N+:24]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH:17]=[CH:16][CH:15]=2)=[CH:10][C:9]=1[NH2:24])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 69592794(4-Naphthalen-1-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester

Product 1

HCID 69592783(2-Amino-4-naphthalen-1-yl-phenyl)-carbamic acid tert.-butyl ester

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

Prepared from (4-naphthalen-1-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example B7) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a white solid (226 mg).

Sources & evidence

ORD record
ord-126eae7a8060405b8f6844ab4632bd54
Source dataset
uspto-grants-2005_11
Patent number
US06960578B2

Reaction notes

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