HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 69592810, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Magnesium Chloride | HCID 5360315 | — |
| Reactant | HCID 22224958 | HCID 22224958 | — |
| Reactant | HCID 23662309 | HCID 23662309 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 69592810 | HCID 69592810 | — |
Reaction Steps
Prepared from 2-imidazol-1-yl-isonicotinoyl chloride hydrochloride [prepared by reaction of tert.-butyl 2-chloroisonicotinoate with imidazole and NaH in DMF at 80° C., treatment with formic acid at 50° C. and reaction with thionylchloride in toluene at 100° C.] and tert.-butyl malonate potassium salt with Et3N and MgCl2 in CH3CN according to general procedure H (method a). Obtained as a brown solid (10.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960578B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-5247e705460f46f4a48f06a7c4459efb |
| Source note | uspto-grants-2005_11 |