HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(3-cyanophenyl)-3-oxopropanoate → {2-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-4-iodo-phenyl}-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(3-cyanophenyl)-3-oxopropanoate | HCID 11622629 | — |
| Reactant | (2-Amino-4-iodo-phenyl)-carbamic acid tert-butyl ester | HCID 69592774 | — |
| Product | {2-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-4-iodo-phenyl}-carbamic acid tert.-butyl ester | HCID 86587990 | 88% |
Reaction Steps
Prepared from (2-amino-4-iodo-phenyl)-carbamic acid tert.-butyl ester (Example G1) (900 mg, 2.7 mmol) and 3-(3-cyano-phenyl)-3-oxo-propionic acid ethyl ester (880 mg, 4.1 mmol) according to the general procedure K. Obtained as a yellow solid (1.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960578B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-4e6fac566a7f4c53a3481f87ffc055ed |
| Source note | uspto-grants-2005_11 |