HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54189546, compound → HCID 86588046, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54189546 | HCID 54189546 | — |
| Reactant | Tert-butyl (3-amino-4'-fluoro-[1,1'-biphenyl]-4-YL)carbamate | HCID 59737201 | — |
| Product | HCID 86588046 | HCID 86588046 | 60.2% |
Reaction Steps
Prepared from (3-amino-4′-fluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example G39) (360 mg, 1.2 mmol) and 3-(3-chloro-thiophen-2-yl)-3-oxo-propionic acid ethyl ester (Example H16) (350 mg, 1.5 mmol) according to the general procedure K. Obtained as a white-yellow solid (353 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960578B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-fcdd39a7b676422582bfad65fa98bdad |
| Source note | uspto-grants-2005_11 |