HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → tert-butyl 2-ethylhydrazinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | tert-Butyl 2-ethylidenehydrazine-1-carboxylate | HCID 57358255 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | tert-butyl 2-ethylhydrazinecarboxylate | HCID 11194489 | 97.5% |
Reaction Steps
A slurry of N′-ethylidene-hydrazinecarboxylic acid tert-butyl ester (5.0 g, 32 mmol), acetic acid (48 μL) and PtO2 (250 mg) in ethanol (50 mL) was shaken under a 40 psi pressure of H2 in a Parr hydrogenator for 24 h. The mixture was filtered through Celite to provide N′-ethylhydrazinecarboxylic acid tert-butyl ester (5 g) as a clear oil. MS (ESI+) for C7H16N2O2 m/z 161.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960664B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-846c360a658f4784b9fa1581d32e86d1 |
| Source note | uspto-grants-2005_11 |