Isocaproic acid → HCID 10186547, compound

HRID 1062333Notes

Reaction equation

HRID 1062333 reaction equation
[NH2:1][C@@H:2]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C@H:3]([OH:16])[CH2:4][N:5]([CH2:14][CH3:15])[NH:6][C:7]([O:9]C(C)(C)C)=O.[CH3:24][CH:25]([CH3:31])[CH2:26][CH2:27]C(O)=O.[CH3:32][S:33]([NH:36][C:37]1[S:38][CH:39]=[C:40]([C:42](O)=[O:43])[N:41]=1)(=[O:35])=[O:34]>>[CH2:17]([C@H:2]([NH:1][C:42]([C:40]1[N:41]=[C:37]([NH:36][S:33]([CH3:32])(=[O:35])=[O:34])[S:38][CH:39]=1)=[O:43])[C@H:3]([OH:16])[CH2:4][N:5]([CH2:14][CH3:15])[NH:6][C:7](=[O:9])[CH2:27][CH2:26][CH:25]([CH3:24])[CH3:31])[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

4

Reactant 3

HCID 12587Isocaproic acidHCID 22051332HCID 22051332, compoundHCID 69611254HCID 69611254, compound

Product 1

HCID 10186547HCID 10186547, compound

Procedure

Synthesized as described above from tert-butyl 2-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-2-ethylhydrazinecarboxylate, 4-methylpentanoic acid and 2-methanesulfonylamino-thiazole-4-carboxylic acid. MS (ESI+) for C23H35N5O5S2 m/z 526.7 (M+H)+.

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-4bfbd442435a443a878acb9456f8dc2e
Source dataset
uspto-grants-2005_11
Patent number
US06960664B2

Reaction notes

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