Pyridine → 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-[(3-methylsulfanyl-propoxyamino)-methyl]-benzamide
Reaction equation
[BH3:39].[F:1][c:2]1[c:3]([NH:24][c:25]2[c:26]([F:32])[cH:27][c:28]([I:31])[cH:29][cH:30]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH:16]=[N:17][O:18][CH2:19][CH2:20][CH2:21][S:22][CH3:23])[c:14]1[F:15].[OH:40][C:41]([CH:42]([Cl:43])[Cl:44])=[O:45].[n:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1>>[F:1][c:2]1[c:3]([NH:24][c:25]2[c:26]([F:32])[cH:27][c:28]([I:31])[cH:29][cH:30]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH2:16][NH:17][O:18][CH2:19][CH2:20][CH2:21][S:22][CH3:23])[c:14]1[F:15]Participants
5
Sources & evidence
- ORD record
- ord-6d56fcc573664731a99e7f3d12818095
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…