Hydrochloric Acid → 356044-81-0

Participants

Reaction Steps

A mixture of 1-tert-butoxycarbonyl-4-(2-fluoroethyl)homopiperazine (550 mg, 2.23 mmol) in 10% aqueous hydrochloric acid (2 mL) and tetrahydrofuran (4 mL) was stirred at room temperature for 2 h, and the reaction mixture was evaporated to dryness under vacuum. Resulting residue was triturated from Et2O/MeOH to afford the titled compound (475 mg, 97%) as a white solid.

Provenance & Evidence