Ethyl cyanoacetate → HCID 178433994, compound

Participants

Reaction Conditions

Reaction Steps

5-Amino-1,3-dimethylpyrazole-4-carboxaldehyde (6.15 g) was dissolved in ethyl cyanoacetate (10 mL), and stirred at 185° C. for 3 hours. The reaction mixture was allowed to cool to room temperature. The precipitated solid was filtered, washed with ethyl acetate, and dried under high vacuum to give 6-hydroxy-1,3-dimethylpyrazolo[5,4-b]pyridine-5-carbonitrile as a white powder.

Provenance & Evidence