Methyl 5-bromovalerate → HCID 67319692, compound
Reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[C:8]([C:10]3[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=3)[N:7]([C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)[C:6]=2[CH:23]=1.[CH3:24][O:25][C:26](=[O:32])[CH2:27][CH2:28][CH2:29][CH2:30]Br>>[CH3:24][O:25][C:26](=[O:32])[CH2:27][CH2:28][CH2:29][CH2:30][O:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[C:8]([C:10]3[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=3)[N:7]([C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)[C:6]=2[CH:23]=1Participants
3
Procedure
6-Hydroxy-1-(4-fluorophenyl)-2-(3-pyridinyl)-1H-benzimidazole was reacted with 5-bromo-pentanoic acid methyl ester according to general operating instructions 3.
Sources & evidence
- ORD record
- ord-91a378aeb121436281a0e87ab6613938
- Source dataset
- uspto-grants-2005_11
- Patent number
- US06962932B2
Reaction notes
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