2-Thiazolamine, 4-(4-methoxyphenyl)-5-(3-pyridinyl)- → [4-(4-Methoxyphenyl)-5-(3-pyridyl)-1,3-thiazol-2-yl]amine hydrochloride

Participants

Role	Name	HCID	Charge
Reactant	2-Thiazolamine, 4-(4-methoxyphenyl)-5-(3-pyridinyl)-	HCID 3024894	—
Reactant	Hydrochloride methanol	HCID 21893726	—
Product	[4-(4-Methoxyphenyl)-5-(3-pyridyl)-1,3-thiazol-2-yl]amine hydrochloride	HCID 13518884	80%

Reaction Steps

[4-(4-Methoxyphenyl)-5-(3-pyridyl)-1,3-thiazol-2-yl]amine (200 mg) was dissolved in 1% hydrochloric acid-methanol (3.2 mL) and the solvent was evaporated. The obtained crude crystals were recrystallized from methanol-ethyl acetate to give the title compound (180 mg, yield 80%).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06962933B1
Source dataset	uspto-grants-2005_11
ORD ID	ord-f1b5d51f519c45178c251dde334f60cd
Source note	uspto-grants-2005_11