HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1062624Generated: November 4, 2026
Ethyl Acetate → 2-Bromo-1-(3,5-dimethylphenyl)-2-(4-pyridyl)ethanone hydrocbromide
https://huagongshe.com/reaction/1062624
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-(3,5-Dimethylphenyl)-2-(4-pyridyl)ethanone | HCID 22282297 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Bromo-1-(3,5-dimethylphenyl)-2-(4-pyridyl)ethanone hydrocbromide | HCID 22282361 | 268.1% |
Reaction Steps
1-(3,5-Dimethylphenyl)-2-(4-pyridyl)ethanone (7.0 g, 31 mmol) was dissolved in acetic acid (35 mL) and bromine (1.6 mL, 31 mmol) was added. The mixture was stirred at 80° C. for 3 h. Ethyl acetate was added to the residue and the precipitated crude crystals were collected by filtration. The crude crystals were washed with ethyl acetate to give the title compound (16 g, yield 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06962933B1 |
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| Source dataset | uspto-grants-2005_11 |
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| ORD ID | ord-6f7af2f2688c4bf982c5924a2bc5786b |
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| Source note | uspto-grants-2005_11 |
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