5-(2,2,3,3,3-Pentafluoro-propoxy)-pyridine-2-carboxylic acid → N-[3-(2-amino-5,5-difluoro-4-methyl-6H-1,3-oxazin-4-yl)-4-fluorophenyl]-5-(2,2,3,3,3-pentafluoropropoxy)pyridine-2-carboxamide
Reaction equation
[F:19][C:20]([CH2:21][O:22][c:23]1[cH:24][cH:25][c:26]([C:29](=[O:30])[OH:31])[n:27][cH:28]1)([C:32]([F:33])([F:34])[F:35])[F:36].[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1)[C:29]([c:26]1[cH:25][cH:24][c:23]([O:22][CH2:21][C:20]([F:19])([C:32]([F:33])([F:34])[F:35])[F:36])[cH:28][n:27]1)=[O:30]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-47af682988894dd5b166f95b7e447bec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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