Trimethylphosphine → 4-Methoxybiphenyl

Participants

Reaction Steps

The procedure was identical to Example 1, with the exception that the nickel catalyst used was derived in situ from a combination of anhydrous nickel acetylacetonate (0.026 g; 5 mol %) and trimethylphosphine (0.20 mL of 1M solution in toluene; 10 mol %). GC analysis of the organic phase of the hydrolyzed reaction sample after 2 h at 60° C. showed the presence of 1.76 mmol (88% yield) of 4-phenylanisole, 0.11 mmol of 4-methoxybenzophenone imine, and no remaining 4-methoxybenzonitrile in the reaction mixture.

Provenance & Evidence