2-Pyridinemethanamine → HCID 85797591, compound

HRID 1063144Notes

Reaction equation

HRID 1063144 reaction equation
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.[Cl:9][C:10]1[CH:15]=[CH:14][N:13]=[C:12]2[CH:16]=[C:17]([C:19]([O-])=[O:20])[S:18][C:11]=12.[Li+]>>[N:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[CH2:2][NH:1][C:19]([C:17]1[S:18][C:11]2[C:12](=[N:13][CH:14]=[CH:15][C:10]=2[Cl:9])[CH:16]=1)=[O:20]

Participants

3

Reactant 2

HCID 195092-PyridinemethanamineHCID 23677819Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate

Product 1

HCID 85797591HCID 85797591, compound

Procedure

The title compound was prepared from 2-aminomethylpyridine and lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate by a procedure analogous to Example 1B. MS: 304/306 (MH+); HPLC Rf: 4.36 min.; HPLC purity: 97%.

Sources & evidence

ORD record
ord-ecc2bdfa264147fb8cc5ae33be4cca56
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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