4-Pyridinemethanamine → HCID 85797600, compound

HRID 1063152Notes

Reaction equation

HRID 1063152 reaction equation
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1.[Cl:9][C:10]1[CH:15]=[CH:14][N:13]=[C:12]2[CH:16]=[C:17]([C:19]([O-])=[O:20])[S:18][C:11]=12.[Li+]>>[N:6]1[CH:7]=[CH:8][C:3]([CH2:2][NH:1][C:19]([C:17]2[S:18][C:11]3[C:12](=[N:13][CH:14]=[CH:15][C:10]=3[Cl:9])[CH:16]=2)=[O:20])=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 773174-PyridinemethanamineHCID 23677819Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate

Product 1

HCID 85797600HCID 85797600, compound

Procedure

The title compound was prepared from 4-aminomethyl pyridine and lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate by a procedure analogous to Example 1B. MS: 304/306 (MH+); HPLC Rf: 4.08 min.; HPLC purity: 78%.

Sources & evidence

ORD record
ord-4e387940db5a48e887d45fb815634742
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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