5-Amino-2-methylindole → HCID 90806323, compound

HRID 1063155Notes

Reaction equation

HRID 1063155 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([NH2:11])=[CH:6][CH:5]=2.[N:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[CH2:18][CH2:19][NH:20][C:21]([C:23]1[S:31][C:30]2[C:25](=[N:26][CH:27]=[CH:28][C:29]=2Cl)[CH:24]=1)=[O:22]>>[N:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[CH2:18][CH2:19][NH:20][C:21]([C:23]1[S:31][C:30]2[C:25](=[N:26][CH:27]=[CH:28][C:29]=2[NH:11][C:7]2[CH:8]=[C:9]3[C:4](=[CH:5][CH:6]=2)[NH:3][C:2]([CH3:1])=[CH:10]3)[CH:24]=1)=[O:22]

Participants

3

Reactant 2

HCID 27339925-Amino-2-methylindoleHCID 85797601HCID 85797601, compound

Product 1

HCID 90806323HCID 90806323, compound

Procedure

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (2-pyridin-2-yl-ethyl)-amide by a procedure analogous to Example 1C. MS: 428 (MH+), HPLC Rf: 4.33 min; HPLC purity 99%.

Sources & evidence

ORD record
ord-e9284e8b93f8495ea807a11a75d5d711
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

Loading…