5-Amino-2-methylindole → HCID 69735852, compound

HRID 1063157Notes

Reaction equation

HRID 1063157 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([NH2:11])=[CH:6][CH:5]=2.[N:12]1[CH:17]=[CH:16][C:15]([NH:18][C:19]([C:21]2[S:29][C:28]3[C:23](=[N:24][CH:25]=[CH:26][C:27]=3Cl)[CH:22]=2)=[O:20])=[CH:14][CH:13]=1>>[N:12]1[CH:17]=[CH:16][C:15]([NH:18][C:19]([C:21]2[S:29][C:28]3[C:23](=[N:24][CH:25]=[CH:26][C:27]=3[NH:11][C:7]3[CH:8]=[C:9]4[C:4](=[CH:5][CH:6]=3)[NH:3][C:2]([CH3:1])=[CH:10]4)[CH:22]=2)=[O:20])=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 27339925-Amino-2-methylindoleHCID 69735855HCID 69735855, compound

Product 1

HCID 69735852HCID 69735852, compound

Procedure

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid pyridin-4-ylamide by a procedure analogous to Example 1C. MS: 400 (MH+); HPLC Rf: 4.24 min.; HPLC purity: 99%.

Sources & evidence

ORD record
ord-beb73919111948b88ce6b403f7fd4925
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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