5-Amino-2-methylindole → HCID 69735739, compound

HRID 1063174Notes

Reaction equation

HRID 1063174 reaction equation
[CH3:1][N:2]([CH2:15][C:16]1[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=1)[C:3]([C:5]1[S:13][C:12]2[C:7](=[N:8][CH:9]=[CH:10][C:11]=2Cl)[CH:6]=1)=[O:4].[CH3:22][C:23]1[NH:24][C:25]2[C:30]([CH:31]=1)=[CH:29][C:28]([NH2:32])=[CH:27][CH:26]=2>>[CH3:1][N:2]([CH2:15][C:16]1[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=1)[C:3]([C:5]1[S:13][C:12]2[C:7](=[N:8][CH:9]=[CH:10][C:11]=2[NH:32][C:28]2[CH:29]=[C:30]3[C:25](=[CH:26][CH:27]=2)[NH:24][C:23]([CH3:22])=[CH:31]3)[CH:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 27339925-Amino-2-methylindoleHCID 69735824HCID 69735824, compound

Product 1

HCID 69735739HCID 69735739, compound

Procedure

The title compound was prepared from 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid methyl-pyridin-4-ylmethyl-amide and 2-methyl-1H-indol-5-ylamine by a method analogous to Example 1C. MS: 428 (MH+); HPLC Rf: 4.26 min; HPLC purity: 93%.

Sources & evidence

ORD record
ord-7d81f4d30f9e4ab8a1224dcb5cbed38b
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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