5-Amino-2-methylindole → HCID 10114770, compound

HRID 1063176Notes

Reaction equation

HRID 1063176 reaction equation
[CH3:1][N:2]([CH2:15][CH2:16][N:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1)[C:3]([C:5]1[S:13][C:12]2[C:7](=[N:8][CH:9]=[CH:10][C:11]=2Cl)[CH:6]=1)=[O:4].[CH3:23][C:24]1[NH:25][C:26]2[C:31]([CH:32]=1)=[CH:30][C:29]([NH2:33])=[CH:28][CH:27]=2>>[CH3:1][N:2]([CH2:15][CH2:16][N:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1)[C:3]([C:5]1[S:13][C:12]2[C:7](=[N:8][CH:9]=[CH:10][C:11]=2[NH:33][C:29]2[CH:30]=[C:31]3[C:26](=[CH:27][CH:28]=2)[NH:25][C:24]([CH3:23])=[CH:32]3)[CH:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 27339925-Amino-2-methylindoleHCID 69735789HCID 69735789, compound

Product 1

HCID 10114770HCID 10114770, compound

Procedure

The title compound was prepared from 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid methyl-(2-morpholin-4-yl-ethyl)-amide and 2-methyl-1H-indol-5-ylamine by a procedure analogous to Example 1C. MS: 450 (MH+), HPLC Rf: 3.58 min.; HPLC purity: 99%.

Sources & evidence

ORD record
ord-631e3eff1f86433e805c028dc5404cf3
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

Loading…