HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(BOC-amino)-3-azabicyclo[3.1.0]hexane → {3-[7-Chloro-thieno[3,2-b]pyridine-2-carbonyl]-3-aza-bicyclo[3.1.0]hex-6-yl}-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(BOC-amino)-3-azabicyclo[3.1.0]hexane | HCID 11148308 | — |
| Reactant | Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate | HCID 23677819 | — |
| Product | {3-[7-Chloro-thieno[3,2-b]pyridine-2-carbonyl]-3-aza-bicyclo[3.1.0]hex-6-yl}-carbamic acid tert-butyl ester | HCID 69735881 | — |
Reaction Steps
The title compound was prepared from (3-aza-bicyclo[3.1.0]hex-6-yl)-carbamic acid tert-butyl ester and lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate by a procedure analogous to Example 1B. MS: 394/396 (MH+); HPLC Rf: 5.30 min.; HPLC purity: 72%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06964961B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-60340b5d11d94c9d9f3336fd9b3ed03f |
| Source note | uspto-grants-2005_11 |