tert-Butyl piperazine-1-carboxylate → HCID 69735871, compound

HRID 1063183Notes

Reaction equation

HRID 1063183 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Cl:14][C:15]1[CH:20]=[CH:19][N:18]=[C:17]2[CH:21]=[C:22]([C:24]([O-])=[O:25])[S:23][C:16]=12.[Li+]>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:24]([C:22]2[S:23][C:16]3[C:17](=[N:18][CH:19]=[CH:20][C:15]=3[Cl:14])[CH:21]=2)=[O:25])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 23677819Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate

Product 1

HCID 69735871HCID 69735871, compound

Procedure

The title compound was prepared from piperazine-1-carboxylic acid tert-butyl ester and lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate by a procedure analogous to Example 1B. MS: 382/384 (MH+); HPLC Rf: 5.72 min.; HPLC purity 94%.

Sources & evidence

ORD record
ord-a1de7e9362a04d22b0eb8af20c481f06
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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