HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxypyrrolidine → (7-Chloro-thieno[3,2-b]pyridin-2-yl)-(3-hydroxy-pyrrolidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxypyrrolidine | HCID 98210 | — |
| Reactant | Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate | HCID 23677819 | — |
| Product | (7-Chloro-thieno[3,2-b]pyridin-2-yl)-(3-hydroxy-pyrrolidin-1-yl)-methanone | HCID 22143479 | — |
Reaction Steps
This compound was prepared from (+/−)-3-hydroxypyrrolidine and lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate by a procedure analogous to Example 1B. MS: 283/285 (MH+); HPLC Rf: 3.44 min.; HPLC purity 91%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06964961B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-7933b80ddd444134b989ab4d3d497337 |
| Source note | uspto-grants-2005_11 |