Methanesulfonyl chloride → HCID 91506565, compound

HRID 1063193Notes

Reaction equation

HRID 1063193 reaction equation
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[NH2:6][CH:7]1[CH2:11][CH2:10][N:9]([C:12]([C:14]2[S:22][C:21]3[C:16](=[N:17][CH:18]=[CH:19][C:20]=3[Cl:23])[CH:15]=2)=[O:13])[CH2:8]1>>[Cl:23][C:20]1[CH:19]=[CH:18][N:17]=[C:16]2[CH:15]=[C:14]([C:12]([N:9]3[CH2:10][CH2:11][CH:7]([NH:6][S:2]([CH3:1])(=[O:4])=[O:3])[CH2:8]3)=[O:13])[S:22][C:21]=12

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 22278662HCID 22278662, compound

Product 1

HCID 91506565HCID 91506565, compound

Procedure

The title compound was prepared from methanesulfonyl chloride and (3-amino-pyrrolidin-1-yl)-(7-chloro-thieno[3,2-b]pyridin-2yl)-methanone by a procedure analogous to Example 64C. MS: 360/362 (MH+); HPLC Rf: 3.22 min.; HPLC purity 98%.

Sources & evidence

ORD record
ord-e4a913917e564fd3af977581ee523af0
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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