5-Amino-2-methylindole → HCID 91500490, compound

HRID 1063194Notes

Reaction equation

HRID 1063194 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[CH:8]=[C:9]([C:11]([N:13]3[CH2:17][CH2:16][CH:15]([NH:18][S:19]([CH3:22])(=[O:21])=[O:20])[CH2:14]3)=[O:12])[S:10][C:3]=12.[CH3:23][C:24]1[NH:25][C:26]2[C:31]([CH:32]=1)=[CH:30][C:29]([NH2:33])=[CH:28][CH:27]=2>>[CH3:23][C:24]1[NH:25][C:26]2[C:31]([CH:32]=1)=[CH:30][C:29]([NH:33][C:2]1[CH:7]=[CH:6][N:5]=[C:4]3[CH:8]=[C:9]([C:11]([N:13]4[CH2:17][CH2:16][CH:15]([NH:18][S:19]([CH3:22])(=[O:21])=[O:20])[CH2:14]4)=[O:12])[S:10][C:3]=13)=[CH:28][CH:27]=2

Participants

3

Reactant 2

HCID 27339925-Amino-2-methylindoleHCID 91506565HCID 91506565, compound

Product 1

HCID 91500490HCID 91500490, compound

Procedure

The title compound was prepared from (+/−)-methanesulfonic acid {1-[7-chloro-thieno[3,2-b]pyridine-2-carbonyl]-pyrrolidin-3-yl}-amide and 2-methyl-1H-indol-5-ylamine by a procedure analogous to Example 1C. MS: 470 (MH+); HPLC Rf: 3.23 min.; HPLC purity 93%.

Sources & evidence

ORD record
ord-a58f86f9b14e40f0b016277470019539
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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