Methanesulfonyl chloride → HCID 91069034, compound

HRID 1063199Notes

Reaction equation

[CH3:1][S:2](Cl)(=[O:4])=[O:3].[CH3:6][NH:7][CH:8]1[CH2:12][CH2:11][N:10]([C:13]([C:15]2[S:23][C:22]3[C:17](=[N:18][CH:19]=[CH:20][C:21]=3[Cl:24])[CH:16]=2)=[O:14])[CH2:9]1>>[CH3:6][N:7]([CH:8]1[CH2:12][CH2:11][N:10]([C:13]([C:15]2[S:23][C:22]3[C:17](=[N:18][CH:19]=[CH:20][C:21]=3[Cl:24])[CH:16]=2)=[O:14])[CH2:9]1)[S:2]([CH3:1])(=[O:4])=[O:3]

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 22278671HCID 22278671, compound

Product 1

HCID 91069034HCID 91069034, compound

Procedure

The title compound was prepared from methanesulfonyl chloride and (3-methylamino-pyrrolidin-1-yl)-(7-chloro-thieno[3,2-b]pyridin-2yl)-methanone by a procedure analogous to Example 64C. MS: 374/376 (MH+); HPLC Rf: 4.14 min.; HPLC purity 98%.

Sources & evidence

ORD record: ord-0239a8708837472299e3542913a5d2a7
Source dataset: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06964961B2

Reaction notes

Loading…