1,4-Dideoxy-1,4-iminothreitol → HCID 23401168, compound

HRID 1063211Notes

Reaction equation

HRID 1063211 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[CH:8]=[C:9]([C:11]([O-:13])=O)[S:10][C:3]=12.[Li+].[NH:15]1[CH2:19][C@H:18]([OH:20])[C@@H:17]([OH:21])[CH2:16]1>>[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[CH:8]=[C:9]([C:11]([N:15]3[CH2:19][C@H:18]([OH:20])[C@@H:17]([OH:21])[CH2:16]3)=[O:13])[S:10][C:3]=12

Participants

3

Reactant 2

HCID 1461981,4-Dideoxy-1,4-iminothreitolHCID 23677819Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate

Product 1

HCID 23401168HCID 23401168, compound

Procedure

The title compound was prepared from lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate and (3S,4S)-pyrrolidine-3,4-diol by a procedure analogous to Example 1B. MS: 299.3/301.3 (MH+); HPLC Rf: 3.091 min.; HPLC purity: 99%.

Sources & evidence

ORD record
ord-48c476c57668498e8a7c3b6748ab6788
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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