1-azetidin-3-ylpyrrolidine → HCID 22278647, compound

HRID 1063226Notes

Reaction equation

HRID 1063226 reaction equation
[NH:1]1[CH2:4][CH:3]([N:5]2[CH2:9][CH2:8][CH2:7][CH2:6]2)[CH2:2]1.[CH3:10][C:11]1[NH:12][C:13]2[C:18]([CH:19]=1)=[CH:17][C:16]([NH:20][C:21]1[CH:26]=[CH:25][N:24]=[C:23]3[CH:27]=[C:28]([C:30](O)=[O:31])[S:29][C:22]=13)=[CH:15][CH:14]=2>>[CH3:10][C:11]1[NH:12][C:13]2[C:18]([CH:19]=1)=[CH:17][C:16]([NH:20][C:21]1[CH:26]=[CH:25][N:24]=[C:23]3[CH:27]=[C:28]([C:30]([N:1]4[CH2:4][CH:3]([N:5]5[CH2:9][CH2:8][CH2:7][CH2:6]5)[CH2:2]4)=[O:31])[S:29][C:22]=13)=[CH:15][CH:14]=2

Participants

3

Reactant 2

HCID 103293031-azetidin-3-ylpyrrolidineHCID 22278637HCID 22278637, compound

Product 1

HCID 22278647HCID 22278647, compound

Procedure

The title compound was prepared from 1-azetidin-3-yl-pyrrolidine and 7-(2-methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid by a procedure analogous to Example 21B. MS: 312 (MH+); HPLC Rf: 3.211 min; HPLC purity: 96%.

Sources & evidence

ORD record
ord-5422f02515e345ed92c3aee25e698e7b
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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