tert-Butyl piperazine-1-carboxylate → HCID 69735871, compound

HRID 1063227Notes

Reaction equation

HRID 1063227 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[CH:8]=[C:9]([C:11]([O-:13])=O)[S:10][C:3]=12.[Li+].[C:15]([O:19][C:20]([N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)=[O:21])([CH3:18])([CH3:17])[CH3:16]>>[C:15]([O:19][C:20]([N:22]1[CH2:27][CH2:26][N:25]([C:11]([C:9]2[S:10][C:3]3[C:4](=[N:5][CH:6]=[CH:7][C:2]=3[Cl:1])[CH:8]=2)=[O:13])[CH2:24][CH2:23]1)=[O:21])([CH3:18])([CH3:16])[CH3:17]

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 23677819Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate

Product 1

HCID 69735871HCID 69735871, compound

Procedure

The title compound was prepared from lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate and piperazine-1-carboxylic acid tert-butyl ester by a procedure analogous to Example 1B. MS: 383 (MH+); HPLC Rf: 5.69; HPLC purity: 99%.

Sources & evidence

ORD record
ord-6feb494269ab408dac824ff1d6b127e1
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

Loading…