HCID 22278860, compound → 4-Dimethylamino-3-ethyl-3-methylpiperidine

Participants

Reaction Steps

A mixture of 20% Pd(OH)2 on carbon (0.7 g) and 1-benzyl-4-dimethylamino-3-ethyl-3-methyl piperidine (6 g, 23 mmol) in methanol (50 ml) was stirred in hydrogen atmosphere (1 atm.) for 48 hr at room temperature. The catalyst was filtered off, washed with methanol and filtrate was concentrated to afford 4-dimethylamino-3-ethyl-3-methylpiperidine. Yield 2.8 (72%), C10H22N2, m/z 171 (M+1).

Provenance & Evidence