2-(Ethylamino)ethanol → HCID 10222543, compound

HRID 1063358Notes

Reaction equation

HRID 1063358 reaction equation
Cl.Br[CH2:3][CH2:4][CH2:5][CH2:6][O:7][CH:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1.Cl[C:15]([O:17][C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=1)=[O:16].[CH2:25]([NH:27][CH2:28][CH2:29][OH:30])[CH3:26]>>[Cl:24][C:21]1[CH:22]=[CH:23][C:18]([O:17][C:15]([N:11]2[CH2:12][CH2:13][CH:8]([O:7][CH2:6][CH2:5][CH2:4][CH2:3][N:27]([CH2:25][CH3:26])[CH2:28][CH2:29][OH:30])[CH2:9][CH2:10]2)=[O:16])=[CH:19][CH:20]=1

Participants

4

Reactant 3

HCID 80722-(Ethylamino)ethanolHCID 1390594-Chlorophenyl chloroformateHCID 85812949HCID 85812949, compound

Product 1

HCID 10222543HCID 10222543, compound

Procedure

In analogy to example 1.4 and 1.5, reaction of 4-(4-Brom-butoxy)-piperidine hydrogen chloride with 4-chlorophenyl chloroformate and 2-ethylamino-ethanol yielded 4-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-butoxy}-piperidine-1-carboxylic acid 4-chlorophenyl ester, MS: 399 (MH+).

Sources & evidence

ORD record
ord-7c03e9fcdd7f41b1b76034a071365ded
Source dataset
uspto-grants-2005_11
Patent number
US06964974B2

Reaction notes

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