Sodium Iodide → HCID 69784064, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 733 mg (2.15 mmol) of 4-(5-Chloro-pent-1-ynyl)-piperidine-1-carboxylic acid 4-chloro-phenyl ester in 20 ml butan-2-one was treated with 650 mg of NaI (4.3 mmol) and heated at 80° C. for 48 h. Evaporation gave crude 4-(5-Iodo-pent-1-ynyl)-piperidine-1-carboxylic acid 4-chloro-phenyl ester, which was used directly for the next step, MS: 431 (M, 1Cl).

Provenance & Evidence