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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 106342Generated: October 26, 2026

Tetrahydrofuran → 2-(2,2,2-Trifluoroethylamino)-4-(4-fluoro-2-methylphenyl)-8-(2,6-difluorophenyl)-8H-pyrido[2,3-d]pyrimidin-7-one

https://huagongshe.com/reaction/106342

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthanamine, 2,2,2-trifluoro-HCID 9773—
Reactant8-(2,6-difluoro-phenyl)-4-(4-fluoro-2-methyl-phenyl)-2-methanesulfonyl-8H-pyrido[2,3-d]pyrimidin-7-oneHCID 59639554—
Product2-(2,2,2-Trifluoroethylamino)-4-(4-fluoro-2-methylphenyl)-8-(2,6-difluorophenyl)-8H-pyrido[2,3-d]pyrimidin-7-oneHCID 59639543—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-20ae0ff391554486a692f4d63c3f8faa
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)