4-(2-[1,3]Dioxan-2-yl-ethyl)-6-(4-fluoro-phenyl)-pyrido[3,2-d]pyrimidin-2-ylamine → 4-Cyclopropyl-6-(4-fluorophenyl)pyrido[3,2-d]pyrimidin-2-amine

HRID 106350Notes

Reaction equation

HRID 106350 reaction equation
[Cl:27][c:28]1[n:29][c:30]([CH:31]2[CH2:32][CH2:33]2)[c:34]2[n:35][c:36](-[c:37]3[cH:38][cH:39][c:40]([F:41])[cH:42][cH:43]3)[cH:44][cH:45][c:46]2[n:47]1.[O:1]1[CH:2]([CH2:7][CH2:8][c:9]2[c:10]3[c:11]([n:12][c:13]([NH2:15])[n:14]2)[cH:16][cH:17][c:18](-[c:20]2[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]2)[n:19]3)[O:6][CH2:5][CH2:4][CH2:3]1>>[CH2:2]1[CH2:7][CH:8]1[c:9]1[c:10]2[c:11]([n:12][c:13]([NH2:15])[n:14]1)[cH:16][cH:17][c:18](-[c:20]1[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]1)[n:19]2

Participants

3

Reactant 2

HCID 249638714-(2-[1,3]Dioxan-2-yl-ethyl)-6-(4-fluoro-phenyl)-pyrido[3,2-d]pyrimidin-2-ylamineHCID 579067542-Chloro-4-cyclopropyl-6-(4-fluoro-phenyl)-pyrido[3,2-d]pyrimidine

Product 1

HCID 249635224-Cyclopropyl-6-(4-fluorophenyl)pyrido[3,2-d]pyrimidin-2-amine

Sources & evidence

ORD record
ord-096d6a63fd2843d3a41a6cc51c4fa39f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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