HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 2-Amino-4-diethylphosphonomethyloxy-6-bromobenzothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 2-Amino-4-diethylphosphonomethyloxybenzothiazole | HCID 54277848 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Amino-4-diethylphosphonomethyloxy-6-bromobenzothiazole | HCID 54527742 | — |
Reaction Steps
A solution of 2-amino-4-(diethylphosphonomethyloxy)benzothiazole (1 mmole) in AcOH (6 mL) was cooled to 10° C. and treated with bromine (1.5 mmole) in AcOH (2 mL). After 5 min the mixture was stirred at room temperature for 2.5 h. The yellow precipitate was collected via filtration and washed with CH2Cl2 to give 2-amino-4-diethylphosphonomethyloxy-6-bromobenzothiazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06965033B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-1cd0cbca867d48b4a7ac33be4baa1f95 |
| Source note | uspto-grants-2005_11 |