HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 1-Chloro-5-methoxy-4-methyl-2-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-Chloro-2-fluoro-5-nitrotoluene | HCID 87593 | — |
| Product | 1-Chloro-5-methoxy-4-methyl-2-nitrobenzene | HCID 21671107 | — |
Reaction Steps
A solution of 2-chloro-4-floro-5-methylnitrobenzene (1 mmole) in DMF (5 mL) was treated with fresh sodium methoxy (1.1 mmole), and the mixture was stirred for 6 h. Evaporation and chromatography gave 2-chloro-4-methoxy-5-methylnitrobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06965033B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-23287deedc514f49b56bdf8455dd4c18 |
| Source note | uspto-grants-2005_11 |